QCan all the tissues of the body use Ketones to generate energy?
A

Ketones (Ketone Bodies) are not used in the liver as energy substrates but can be used efficiently by the brain, heart and other tissues. Neurons can use ketones as energy substrates and it is said that the efficiency by which ATP can be generated using the ketone versus glucose may be in the order exceeding 38% more ATP per unit ketone carbon. Peripheral cells of the body including muscle can utilize the ketone to generate ATP as well and their uptake by cells is independent of insulin. In addition research shows that ketones (elevated serum ketone) provide the signal to spare lean muscle in the face of stress.


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